Hutchinson’s Sign in Subungual Melanoma In Situ

Published September 3, 2025

N Engl J Med 2025;393: e13

DOI: 10.1056/NEJMicm2504151

Abstract

A 71-year-old man presented with a 2-year history of a darkening line on his left thumbnail. Also noted were a brown discoloration of the left thumbnail and hyperpigmentation of the proximal nail fold and tip of the thumb.

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Published online: September 3, 2025

Published in issue: September 4, 2025

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